The nucleus on the right has been hybridized to probes for chromosomes 18 (aqua), X (green), and Y (red). The nucleus on the left has been hybridized to probes for chromosomes 13 (green), and 21 (red) and clearly has three red signals. This Aneuploid Screen test shows a female fetus with trisomy-21. Since there are two signals each for chromosomes 13, 18, and 21 and one signal each for the X and Y chromosome this fetus is a normal male with respect to the Aneuploid Screen test. The nucleus on the left has been hybridized to probes for chromosomes 13 (green), and 21 (red). This is an example of the Aneuploid Screen test, where interphase nuclei from amniotic fluid cells have been combined with DNA probes for chromosomes 13, 18, 21, X, and Y. Individual chromosomes can be selected and exported to the sample Management ( Metaclass Database) to add comments to the final results and printable report. *mtc session file or * bpm image can be saved and recalled. – Damaged chromosomes bands can be highlighted in the karyotype study. – Best Brightness and contrast can be modified and automatically obtained. – Obtaining the specular image, as well as Magnification of the individual chromosomes is available – Separation: When two chromosomes are joint in an extreme, can be automatically – Superimpositions: A chromosome appears superimposed to other in one part Unclassified chromosomes can be automatically corrected, or manually if desired, for the following: The module offers 3 views on the screen: Metaphase view, Karyotype and Unclassified chromosomes window marked with 0 Threshold can be modified to improve the captured image quality
Karyotype study is analysed under brightfield microscopy.
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